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Erysiphe cichoracearum (also called Golovinomyces cichoracearum (Belanger et al. 2002) is a powdery mildew that infects four major cucurbit crop species at CASFS and world wide: melon (Cucumis melo), cucumber (Cucumis sativus), squash (including guards, pumpkins, and zucchini) (Cucurbita pepo, C. peop ssp. ovifera, C. pepo ssp. fraterna), and watermelon (Citrullus lanatus) (Belanger et al. 2000). It has over 300 hosts (Westcott 2001), mostly cucurbits and composites including Helianthus spp. (Sunflower) at CASFS. Other hosts include lettuce, endive, Jerusalem artichoke, pepper, potato, salsify, Echinacea, eucalyptus,begonia, calendula, chrysanthemum, clematis, coreopsis, phlox, salvia, stokesia and zinnia. Agrios (1997) estimates that among crops and ornamentals, losses due to reduced photosynthesis, plant growth, and crop yield (by as much as 20 or 40 percent) by powdery mildew are probably greater than losses caused by any other single type of plant disease.
Symptoms
E. cichoracearum, along with all powdery mildews, is an obligate biotroph and thus does not kill the hosts. Rather, the fungus utilizes host nutrients and in the process reduces growth and yield by impairing photosynthesis and increasing respiration and transpiration (Agrios 1997).
Besides these symptoms, signs of powdery mildew are most apparent. White mycelium and conidiophores with long chains of white conidia grow on the sunny host surface, as though the surface was sprinkled with white powder (Macrophoto 4a).
Life History and Epidemiology
Conidial germination is sparked by the separation of the conidia from the condiophore and by the chemical recognition of having landed on a suitable host (Belanger et al. 2002). Many studies have been done on the development of E. pisi, so for the purpose of this description it is assumed to have a similar development to E. cichoracearum. Conidia germinate to produce a germ tube that elongates to form a septum which then differentiates into an appresorium (Kunoh et al. 1979; Sing and Singh 1983, Carver et al. 1996). A penetration peg then develops from the appresorium that penetrates the host cuticle and into the epidermal cell (Belanger et al. 2002). After penetration, the tip of the hyphal penetration peg enters the cell and forms a specialized absorption structure termed the haustorium, which is partially responsible for the transport of nutrients from the host into the haustorium (Spencer-Phillips and Gay 1981, Gay et al. 1987). Meanwhile, on the leaf surface of the host, nutrients taken up by the haustorium contribute to the white mycelium that continues to grow and develop conidiophores with oblong shaped conidia attached in chains (Microphoto 4A-B). Conidia are air-dispersed and ready to be liberated and infect more host tissue. On an individual leaf, powdery mildew distribution can either occur as small patches or to uniformly blanket the leaf.
The powdery mildews are common in cool or warm, humid areas, but are most pervasive in warm, dry climates (Agrios 1997). This is possible because germination can occur without any moisture on the leaf surface, as long as the relative humidity is high. When conditions become very dry, cleistothecia are produced on the leaf surface (Microphoto 4C). Powdery mildew species are most easily differentiated by the morphology of the cleistothecium. E. cichoracearum produces a cleistothecium of about 100 micrometers in diameter with non-ornamented appendages. Each cleistothecium contains asci containing two ascospores (Belanger et al. 2002).

Disease Management

Resistant Cultivars. Powdery mildew resistant varieties of Cucumis spp. and summer and winter squash (Cucurbita spp.) are available in seed catalogues (Belanger et al. 2000). Successful breeding for resistance in Cucurbita have stemmed partially from the transfer of dominant resistant genes in a wild tropical species (C. lundelliana into C. pepo (Rhodes 1959). One of the highest degrees of resistance ever reported was in a cross between Cucummis okeechobeensis ssp. martinezii and C. moschata ‘Butternut’(Munger 1976) which created the progenitors of all commercial resistance now in use in C. pepo and C. moschata (Belanger 2000). Tolerant hybrids are produced by crossing a highly resistant with a less resistant species, however total resistance is only achieved when both parents are highly resistant (Belanger et al. 2000). Taste tests have ranked powdery mildew resistant cucurbita varieties as being “sweeter and better tasting than susceptible parents” (Munger, Moriarty, and Jahn, unpublished data in Belanger et al. 2000. p.246).

Organic Products
Elemental sulfur is effective against powdery mildew (Belanger et al. 2000, Agrios 1997, Westcott 2001), but it can also interfere with other agroecological goals such as maintaining natural herbivore predators. It may also be phytotoxic in a greenhouse environment with temperatures above 27 degrees C (Bellanger et al. 2000).

Biological
The bacterium Bacillus subtilis is registered and commercially available (as Serenade company) and has been shown to be parasitic on powdery mildew or to activate induced resistance in the host (Highland 2000).

The fungus Ampelomyces quisqualis, registered and commercially available (AQ-10), has been shown to be a very effective control of several species of Erysiphales (Sztejnbert et al. 1989, Kiss 1997), and especially under very high humidity. Jarvis and Slingsby (1997) proposed combining application of A. quisqualis with water spraying in dryer conditions. A. quisqualis parasitizes powdery mildew by colonizing hyphae and conidiophores and forming pycnidia within the conidiophores (Hashioka and Nakai), and possibly within the cleistothecia (of E. necator (syn. Uncinula necator) (Kiss 1997).

Other products
Paraffin oil and other oils act as a protectants (Phillip et al. 1990, McGrath and Shishkoff 2000).

Detergents act as protectants and fungicides (Cohen et al. 1996).

Plant extracts of Reynoutria sachalinensis (Mildana) and compost extracts have also been shown to induce host resistance (Daayf et al. 1995, Samerski and Weltzien 1988).

Other inorganic products include potassium bicarbonate, baking soda, soluble silicon, and clay (Belanger et al. 2000).

Future Prospects
A number of additional fungi are also parasitic on powdery mildew and show potential for augmentative biological control, these include: including Verticillium leanii, Cladosporium spp., Acremonium alternatum, Tilletiopsis spp., Pseudozyma rugulosa, and P. flocculosa (Sporodex). The arthropod Orthotydeus lambi is also parasitic.

CASFS Notes:

In an interview, Jim Leap (CASFS Farm Manager, 2003) commented that in a bad year, a 50% yield may be lost to powdery mildew. Furthermore, he mentioned that late August fogs and late plantings (after June 1st ) noticeably worsen the infection.

Literature cited
Belanger, R.R., Bushnell, W.R., Dik, A.J., Carver, T.L.W. Eds. 2002. The Powdery Mildews: A comprehensive treatise. The American Phytopathological Society, Minnesota.

Carver, T.L.W., Ingerson, S.M., and Thomas, B.J. 1996. Influences of host surface features on development of Erysiphe graminis and Erysiphe pisi. Pages 255-266 in: Plant Cuticles-An Integrated Functional Approach. G. Kersteins, ed. BIOS Scientific Publishers, Oxford.

Cohen, R., Shtienbert, D., and Edelstein, M. 1996. Suppression of powdery mildew (Sphaerotheca fuliginea) in cucumber by the detergent Zohjar LQ-215. Eur. J. Plant Pathol. 102:69-75.

Daayf, F., Schmitt, A., and Belanger, R.R. 1995. The effects of plant extracts of Reynoutria saccalinensis on powdery mildew development and leaf physiology of long English cucumber. Plant Disease. 79:577-580.

Gay, J.L. and Manners, J.M. 1987. Dynamic experiemental evidence for the plasma membrane ATPase domain hypothesis of haustorial transport and for ionic coupling of the haustorium of Erysiphe graminis to the host cell (Hordeum vulgare). New Phytol. 107:541-548.

Glazebrook, J., Rogers E.E., and Ausubel F.M. 1997. Use of Arabidopsis for genetic dissection of plant defense responses. Annu. Rev. Genet. 31:547-569.

Hajlaoui, M.R., Benhamou, N., and Belanger, R.R. 1991. Cytochemical aspects of fungal penetration, haustorium formation and interfacial material in rose leaves infected by Sphaerothecia pannosa var. rosae. Physiol. Mol. Plant Pathol. 39:341-355.

Kunoh, H., Itoh, O., Kohno, M., and Ishizaki, H. 1979. Are primary germ tubes of conidia unique to Erysiphe graminis? Annals of Phytopathology. Soc. Jpn. 45:675-682.

Highland, H.B. 2000.AgraQuests search for Serenade: The isolation and development of a new biopesticide for plant protection. (Abstract) Phytopathology. 90:S101.

Jarvis, W.R., and Slingsby, K. 1997. The control of powdery mildew of greenhouse cucumber by water sprays and Ampelomyces quisqualis. Plant Disease. Rep. 61: 728-730.

Kiss, L. 1997. Graminicolous powdery mildew fungi as new natural host of Ampelomyces parasites. Canadian Journal of botany. 75:680-683.

McGrath, M.T., and Shishkoff, N. 2000. Control of cucurbit powdery mildew with JMS Stylet-oil. Plant Disease. 84:989-993.

Samerski, C., and Weltzein, H.C. 1988. Untersuchungen zur Wirkung und Wirkungsmechanismen von Kompostextrakten im Pathosystem Gurke Echter

Gurkenmehltau (Spaerotheca fuliginea). Meded. Fac. Landbouwwet. Rijksuniv. Gent. 53:373-377.

Philipp, W.D., Beuther, E., Hermann, D., Keinkert, E., Oberwalder, C., Schmidtke, M., and Straub, B. 1990. Formulation of the powdery mildew hyperparasite.Ampelomyces quisqualis Cex. Z. Pflanzenkrankh. Pflanzenschutz. 97:120-132. Adam L. and S.C.
Singh, U.P., and H.B. Singh. 1983. Development of Erysiphe pisi on susceptible and resistant cultivars of pea. Trans. Br. Mycol. Soc. 81:275-278.

Spencer-Phillips, P.T.N, and J.L. Gay. 1981. Domains of ATPase in plasma membranes and transport through infected plant cells. New Phytol. 89:393-400.

Somerville. 1996. Genetic characterization of five powdery mildew diseases resistance loci in Arabidopsis thaliana. Plant J. 9:341-356.

Sztejnbert, A., Galper, S., Mazar, S., and Lisker, N. 1989. Ampelomyces quisqualis for biological and integrated control of powdery mildews in Israel. Journal of Phytopathology. 124:285-289.